In the News

The Clumps of Brain Cells That Can Play Pac-Man
What they mean for medicine and perhaps the future of AI data centers.
28bio’s Endurance Study Meets Primary Endpoint, Showing CNS-3D Brain Organoids Predict Clinical Seizure Liability
28bio reports Endurance Study results showing brain organoids predict clinical seizure liability with 83% sensitivity and 89% specificity.
Accelerating Organoid Adoption Set to Transform Cancer Drugs
When asked about the biggest obstacles preventing organoids from reaching their full potential, Alif Saleh, CEO of 28bio, emphasizes that adoption, not technology, is the primary hurdle, particularly in drug discovery, where a staggering 95% failure rate is accepted as the norm.

Spotlights

Modeling Myelination and Therapeutic Response in Demyelinating Disorders
CNS-3D and PNS-3D organoids support authentic myelin formation and enable high-throughput measurement of myelination for therapeutic screening.
Organoid Intelligence Offers New Evidence of Learning-related Activity in Human Neural Tissue
Human-derived neural networks can exhibit measurable markers of learning and memory processes.
Organoid Neurotoxicity Testing Embraced by FDA and NIH
Scientists and regulators have long acknowledged the weaknesses in traditional methods used to identify drugs that may harm the central nervous system.

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Case Studies

Takeda Implements CNS-3D Organoids for Preclinical Neurotoxicity Assessment
CNS-3D organoids provide a human-relevant context for the detection of compound-induced neurotoxicity, supports multiplexed endpoint analysis, and reduces reliance on animal testing.

Takeda’s Validated Method for CNS Safety

Learn how CNS-3D brain organoids deliver 7.4× better clinical predictivity than animal models in this on-demand webinar with Takeda’s Investigative Toxicology team.